Glucose Intolerance Upper Body Obesity

Kaplan has had the good sense needed to notice the obvious. All these conditions characteristically occur in subjects with high insulin levels, and, moreover, these conditions are very likely to coexist in the same person. Thirty five million people in the United States are obese (20% over ideal body weight), and 40 million people are hypertensive. Among the obese, hypertension is three times more common than among the non obese. High triglyceride levels are twice as common among the obese as among the non obese. The association is even stronger if one measures patients with upper body obesity. The paunch so characteristic of the middle aged man is closely related to metabolic factors that put him at risk for a heart attack.

If you still wonder just how strong these associations are, listen to a statement made by Dr. Albert Rocchini, a medical scientist at the University of Minnesota. He writes: âœIt has been estimated that by the fifth decade of life, 85% of diabetic individuals are hypertensive and obese, 80% of obese subjects have abnormal glucose tolerance and are hypertensive, and 67% of hypertensive subjects are both diabetic and obese.â

It is now known that in all these conditions, hyperinsulinism is generally found. In fact, when I first meet an overweight patient, I expect to learn from blood chemistries that the patient has high triglycerides, glucose intolerance, and high insulin levels, and my misgivings are seldom disappointed. Of course, I am more pleased by the fact that these…

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