Kimberly Williams 2015
Celebrity Name Kimberly Williams-Paisley
Kimberly Williams Birth= September 14, 1971
Place Birth Kimberly Williams= Rye, NY
Occupations Kimberly Williams = Actress
Kimberly Williams Relationship on= Married to Brad Paisley
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Kimberly Williams on dopamine hypothesis the influential theory that schizophrenia is caused by an excess of dopamine in the brain, due either to an overproduction of dopamine or a deficiency of the enzyme needed to convert dopamine to norepinephrine (adrenaline). There is some supporting pharmacological and biochemical evidence for this hypothesis, and it is still widely discussed and promoted, particularly in a revised form that postulates the involvement in schizophrenia of both an increased mesolimbic and a decreased pre-frontal dopaminergic activity. See also GLUTAMATE HYPOTHESIS. dopaminergic adj. responding to, releasing, or otherwise involving dopamine. For example, a dopaminergic neuron is any neuron in the brain or other parts of the central nervous system for which dopamine serves as the principal neurotransmitter. Three major tracts of dopamine-containing neurons are classically described: the mesolimbic-mesocortical tract, in which excess dopamine activity is hypothesized to be associated with positive and negative symptoms of schizophrenia; the nigrostriatal tract, which is involved in motor functions and Parkinson’s disease; and the tuberoinfundibular pathway, a local circuit in the hypothalamus that is involved in the regulation of the pituitary hormone prolactin. Kimberly Williams 2016.